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Ruiyang Ge (蓋瑞洋), PhD


I am a biomedical engineer and computational neuroscientist with specialized training and expertise in computational brain health and neuroinformatics. I am a Tenured Associate Professor affiliated with the Institute of Artificial Intelligence and Brain Sciences (IAIBS) and the Department of Computer Science at the University of Macau (UM). Before joining UM, I was affiliated with the Department of Psychiatry and the Djavad Mowafaghian Centre for Brain Health at the University of British Columbia.

Research Interests

  • AI/Machine Learning
  • Computational Psychiatry
  • Human Mental Health
  • Neuroinformatics
  • Personalized Neuroimaging
  • Therapeutic Neuromodulation

My research sits at the intersection of biomedical informatics, data science, and precision mental health. With a background in biomedical engineering (B.Eng.) and computer science (Ph.D.), I develop computational methods that transform complex, multi-scale health data, including neuroimaging, physiological signals, and healthcare data, into actionable insights and tools for healthcare delivery and public health. The long-term goal of my research is to advance precision and translational biomedical informatics.

News and Updates

  • September 2026: I am currently recruiting two PhD students to join my group at the University of Macau, with an expected start date of September 2027. You can find details here. Contact me if you are interested.
  • July 2026: Our work investigating lifestyle and brainAGE in adult depression has been published in the Translational Psychiatry (5-year IF=7.8)!
  • June 2026: Our work investigating the acute perturbations of whole-brain and triple-network connectivity during Low-Frequency-Right TMS for treatment resistant depression has been published in the Neuromodulation (5-year IF=3.6)!
  • May 2026: Our work validating the generalizability of the CentileBrain models across ethnoracially diverse populations has been published in the Proceedings of the National Academy of Sciences (5-year IF=10.6)!
  • May 2026: Our work investigating the brain morphology features in anorexia nervosa and its subtypes has been published in the Plos Medicine (5-year IF=11.6)!
  • April 2026: Our work appraising neuroimaging-based clustering studies in schizophrenia and examining whether brain-derived subtypes are reproducible, biologically valid, and clinically meaningful has been published in the Biological Psychiatry: Global Open Science (5-year IF=3.9)!
  • Feb 2026: Our work reviewing neuroimaging-derived brain age and subtyping in adolescent major depressive disorder has been published in Neuroscience & Biobehavioral Reviews (5-year IF=9.3) and Nature Communications (5-year IF=17.2)!
  • Jan 2026: We received an SOBP Special Project grant for our Translational Neuroimaging Educational Program, see you at the 2026 SOBP Annual Meeting @ NYC.
  • Oct 2025: I am honored to receive the ACNP Global Scholarship!
  • Sep 2025: Our CentileBrain project has been awarded a NIMH R01 grant!
  • Aug 2025: Our collaboration "Episode-specific cortical functional connectome reorganization and neurobiological correlates in bipolar disorder: a cross-sectional study" has been published online in BMC Medicine! Huge congratulations to Xiaobo on this fantastic achievement!
  • April 2025: We successfully organized an educational session and participated in two symposia at the 2025 Society of Biological Psychiatry (SOBP) Annual Meeting.
  • Feb 2025: I will be giving a talk titled "CentileBrain: Normative Brain Modeling and Applications in Psychiatric Disorders" on Feb 6th as part of the UBC IMH PROGRESS Webinar Series.
  • Jan 2025: Our work on personlized neuroimaging for mental health has been highlighted at UBC Medicine PATHWAYS.
  • Jan 2025: Our Translational Neuroimaging Educational Program has been awarded a Special Projects Funding for the Society of Biological Psychiatry (SOBP) Annual Meeting. See you in Toronto in April 2025!
  • Dec 2024: We are pleased to announce that two of our symposium proposals have been successfully accepted for 2025 Society of Biological Psychiatry (SOBP) Annual Meeting.
  • July 2024: Our team has been awarded a CIHR Project Grant!
  • July 2024: Our work on brain-age prediction "Brain age prediction: Systematic evaluation of site effects, and sample age range and size" has been published online in Human Brain Mapping (5-year IF=4.7)! Congratulations to Yuetong and Hao Qi for their first 1st-author publication!
  • June 2024: Our co-authored paper "Brain responses to intermittent fasting and the healthy living diet in older adults" has been published online in Cell Metabolism (5-year IF=31.2).
  • March 2024: Our CentileBrain technical paper "Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation" has been published online in Lancet Digital Health (5-year IF=27.7), and has been highlighted by the Brain & Behavior Research Foundation.